Born in St. Louis, Marquise hails from a musical family deeply rooted in the Blues. He spent his early teenage years in St. Louis mentoring under the late great Blues legend, N.E.A. Heritage Fellowship recipient, and Grammy Award winner Henry James Townsend. Marquise's talents have earned him performing rights with some of America's most notable blues performers such as blues legends B.B. King, Pinetop Perkins, and David "Honeyboy" Edwards. He has also performed at dozens of festivals as well as has toured all throughout Europe.
Knox's debut album "Manchild" was nominated for a Blues Music Award for Best New Artist Debut. The album was recorded when he was 16 with world renowned guitarist Michael Burks and his band. The release received worldwide acclaim, including Living Blues’ Best Debut Artist Award and a Blues Music Award nomination for Best Debut Artist.